hmmm......
Tobacco firm research linked cot death to passive smokingDocuments reveal that original report by British consultant was modified after intervention by Philip Morris
Antony Barnett, public affairs editor
Sunday March 27, 2005
Observer
Research
commissioned by the tobacco giant Philip Morris found that cot death
was linked to passive smoking, fuelling the debate on a ban in public
places as the dangers of 'second-hand smoke' become irrefutable.
A
draft report was later modified to say the links were 'difficult to
quantify', raising concerns that the company tried to influence the
study findings.
The
link between cot death and babies who live in homes where adults smoke
has been strengthening over the past decade. This year, a report by the
government's scientific committee on tobacco and health said children
exposed to cigarette smoke were at 'greater risk' of cot death.
The
first drafts of the study emerged after researchers at the University
of California trawled through company documents released as a result of
lawsuits in the US. Their findings have just been published in the
journal Pediatrics.
The
report was written by the British toxicology consultant Dr Frank
Sullivan. When he concluded that passive smoking was a possible cause
of cot death, or sudden infant death syndrome, company scientists tried
to persuaded him to change his mind, supplying him with evidence to
suggest that the links were 'unproven'.
As
a result of interventions by Philip Morris - the world's biggest
tobacco firm - Sullivan modified his findings. His final study was
published in 2001 in an influential scientific journal, without any
indication of the full role played by the tobacco giant.
The
authors claim that the company documents reveal that the Sullivan study
was part of an attempt by Philip Morris to sway public policy about
smoking around children.
In
the early 1990s, Philip Morris was trying to counter the view that
tobacco smoke could cause cot death. Tobacco bosses feared that such
evidence would create a powerful argument for smoke-free areas in the
home and public places. Stan Glantz, professor of medicine at the
University of California, said: 'Their aim was to use this study to
subtly manipulate public opinion. By [using] the scientific literature,
they can create doubt and confusion among doctors and health officials
over the debate about smoking around children.'
In
1997, Philip Morris commissioned Sullivan to write a review of all the
known risk factors of sudden infant death syndrome. Sullivan was an
expert on birth deformities and had advised the British government on
the impact of chemicals on human reproduction. There is no suggestion
that he was knowingly part of any plan improperly to shift public
policy.
For
Philip Morris, Sullivan was an ideal author because he had also been a
consultant to the cigarette firm Rothmans. A memo said he had
'excellent credentials'.
Sullivan's
consulting fees from Philip Morris were £800 a day and the company
budgeted between £25,000 and £50,000 for his study. The contract stated
that Sullivan would remain free to publish the final version without
restriction by Philip Morris.
Sullivan's
original draft said that not only does a mother smoking during
pregnancy increase the risk of cot death, but so also does exposing a
newborn to smoke: 'The evidence overall suggests that both pre-natal
and post-natal maternal smoking exert independent effects.'
His
final draft included amendments suggested by company scientists which
played down the role of smoking and particularly the role of
second-hand smoke.
At
the suggestion of Philip Morris, he added two paragraphs about a 1999
Tasmanian study of cot death that found no conclusive link between
second-hand smoke and cot death. A company scientist told Sullivan: 'I
think that this paper is extremely important and I also think that, if
at all possible, it ought to be included in your review.'
After
Philip Morris's interventions, Sullivan changed his conclusion that
passive smoking was an independent risk factor for cot death. He argued
that, although smoking during pregnancy raised the risk of cot death,
the threat of passive smoking was 'less well-established'. His final
article, published in the Journal of Paediatric and Perinatal
Epidemiology in 2001, stated the relationship was 'difficult to
quantify'.
Sullivan
said of Philip Morris: 'It is true they suggested I looked at some
other studies and made comments on my work, but they were entitled to
do that. Any changes that were subsequently made were down to me and me
alone.'
He
said he stood by his conclusions that the risks posed by passive
smoking were 'difficult to quantify'. The problem was that babies who
came into contact with second-hand smoke were normally exposed to it
because their mothers smoked during pregnancy. In cot death, it was
difficult to establish the precise cause.
Nobody
at Philip Morris could be contacted, but a statement said people should
be 'guided by the conclusions of public health officials' regarding
passive smoking.
· Additional research by Jason Rodrigues.
Cot death: the facts
Cot death is the industrial world's most common cause of infant death.
In 2003, 175 babies died of cot death in England and Wales.
According
to the Office for National Statistics cot deaths are four times more
likely where babies are born outside marriage. Within marriage, cot
death is three times more likely where the father is a manual worker.
It also occurs more among mothers under 20.
Low-weight babies are also at greater risk.
A
European study found a range of risk factors including babies' heads
being covered in bedding and sleeping under a duvet. Out of 10 deaths,
six could probably be attributed to lying babies on their front or side.